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2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide图片
CAS NO:2653-16-9
包装与价格:
包装价格(元)
100mg询价
250mg询价
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1 g询价

A synthetic intermediate
Cas No.2653-16-9
别名2-氯-N-甲基-N-(4-硝基苯基)乙酰胺
Canonical SMILESO=C(CCl)N(C)C1=CC=C([N+]([O-])=O)C=C1
分子式C9H9ClN2O3
分子量228.6
溶解度DMF: 5 mg/ml,DMSO: 11 mg/ml,PBS (pH 7.2): 0.25 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide is a synthetic intermediate.1It has been used in the synthesis of maternal embryonic leucine zipper kinase (MELK) inhibitors with anticancer activity.

1.Edupuganti, R., Taliaferro, J.M., Wang, Q., et al.Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growthBioorg. Med. Chem.25(9)2609-2616(2017)

 
 
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