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BAY-179
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BAY-179图片
包装与价格:
包装价格(元)
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BAY-179 是一种有效的、选择性的、物种交叉反应的复合物 I 抑制剂 (IC50=79 μM)。
Canonical SMILESC12=NC=CC=C1NC(CN3CCC(C4=NC(C5=CC6=C(C=CC=C6)O5)=CS4)CC3)=N2
分子式C23H21N5OS
分子量415.5
溶解度DMF: Slightly soluble,DMSO: Slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BAY-179 is an inhibitor of mitochondrial complex I, also known as NADH dehydrogenase (IC50s = 79, 38, 27, and 47 nM for the human, mouse, rat, and dog enzymes, respectively).1See theStructural Genomics Consortium (SGC)website for more information.

1.Mowat, J., Ehrmann, A.H.M., Christian, S., et al.Identification of the highly active, species cross-reactive complex I inhibitor BAY-179ACS Med. Chem. Lett.13(3)348-357(2022)

 
 
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