A metabolite of omeprazole
| Cas No. | 176219-04-8 |
| 别名 | 奥美拉唑N-氧化物 |
| Canonical SMILES | O=S(C1=NC2=CC=C(C=C2N1)OC)CC3=C(C)C(OC)=C(C)C=[N]3=O |
| 分子式 | C17H19N3O4S |
| 分子量 | 361.4 |
| 溶解度 | DMF: insol,DMSO: 1 mg/ml,Ethanol: insol,PBS (pH 7.2): insol |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Omeprazole N-oxide is a metabolite of the gastric proton pump inhibitor omeprazole .1It is also a potential impurity found in commercial preparations of omeprazole.2 1.Seshadri, R.K., Raghavaraju, T.V., and Chakravarthy, I.E.A single gradient stability-indicating reversed-phase LC method for the estimation of impurities in omeprazole and domperidone capsulesSci. Pharm.81(2)437-438(2013)
2.Shirasaka, Y., Sager, J.E., Lutz, J.D., et al.Inhibition of CYP2C19 and CYP3A4 by omeprazole metabolites and their contribution to drug-drug interactionsDrug Metab. Dispos.41(7)1414-1424(2013) |
