A derivative of INH1 with anticancer activity
| Cas No. | 560103-80-2 |
| 别名 | N-[4-(2,4-二甲苯基)-2-噻唑基]-4-吡啶甲酰胺 |
| Canonical SMILES | CC1=C(C=CC(C)=C1)C2=CSC(NC(C3=CC=NC=C3)=O)=N2 |
| 分子式 | C17H15N3OS |
| 分子量 | 309.4 |
| 溶解度 | DMSO: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide is a derivative of INH1 with anticancer activity.1It is cytotoxic to MDA-MB-231, MDA-MB-488, HeLa, and K562 cells (IC50s = 1.1, 3.4, 1.6, and 1.2 µM, respectively). 1.Qiu, X.-L., Li, G., Wu, G., et al.Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analoguesJ. Med. Chem.52(6)1757-1767(2009) |
![N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide图片](http://www.cnprot.com/data/daily/2023/01/11/140014_517094_umcs_1047296.png)