DB2115 (tertahydrochloride) 是骨髓主调节因子 PU.1 的有效抑制剂。DB2115 (tertahydrochloride) 具有治疗癌症的潜力,包括白血病等血液系统癌症,以及与PU. 1 功能障碍相关的其他疾病 (信息来自专利 WO2017223260A1,compound DB2115)。
Cas No. | 1366126-19-3 |
分子式 | C32H34Cl4N8O2 |
分子量 | 704.48 |
溶解度 | DMSO : 10 mg/mL (14.19 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 80°C) |
储存条件 | 4°C, away from moisture |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | DB2115 (tertahydrochloride) is a potent inhibitor of myeloid master regulator PU.1. DB2115 (tertahydrochloride) has the potential for the treatment of cancers, including hematologic cancers such as leukemia, as well as other conditions associated with PU. 1 dysfunction (extracted from patent WO2017223260A1, compound DB2115) [1]. [1]. W. David Wilson, et al. Pu.1 inhibitors. Patent WO2017223260A1. |