CX-6258 HCl 是一种有效的激酶选择性泛 Pim 激酶抑制剂，对 Pim-1、Pim-2 和 Pim-3 的 IC50 分别为 5 nM、25 nM 和 16 nM。
| Cas No. | 1353859-00-3 |
| 别名 | Pim-Kinase Inhibitor X |
| Canonical SMILES | CN1CCCN(CC1)C(=O)c1cccc(c1)c1ccc(o1)/C=C/1\c2c(ccc(c2)Cl)NC1=O.Cl |
| 分子式 | C26H24ClN3O3·HCl |
| 分子量 | 498.4 |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CX-6258 HCl is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM). Haddach M, et al. ACS Medicinal Chemistry Letters, 3 (2) , 135-139 |
