CBP/p300-IN-1是CBP/EP300溴结构域抑制剂。
| Cas No. | 2443789-32-8 |
| Canonical SMILES | CC(N1C2=CC=C(OC)C=C2C(C(NC3=C(F)C=CC(C(OC(C)(C)C)=O)=C3)=O)=C1)=O |
| 分子式 | C23H23FN2O5 |
| 分子量 | 426.44 |
| 溶解度 | DMSO: 62.5 mg/mL (146.56 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CBP/p300-IN-1 is a CBP/EP300 bromodomain inhibitor. [1]. Xiang Q, et al. Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer. Eur J Med Chem. 2018 Mar 10;147:238-252. |
