T-3764518 是新颖高效的硬脂酰辅酶A去饱和酶 (SCD) 抑制剂,IC50 为4.7 nM。
Cas No. | 1809151-56-1 |
分子式 | C20H17F6N5O2 |
分子量 | 473.37 |
溶解度 | DMSO : 95 mg/mL (200.69 mM; Need ultrasonic) |
储存条件 | 4°C, away from moisture and light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | T-3764518 is a novel and potent stearoyl coenzyme A desaturase (SCD) inhibitor with an IC50 of 4.7 nM. [1]. Imamura K, et al. Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents. Bioorg Med Chem. 2017 Jul 15;25(14):3768-3779. |