| CAS NO: | 915365-57-0 |
| Cas No. | 915365-57-0 |
| 别名 | 8-C氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-[2-(六氢-1H-氮杂-1-基)乙基]-1H-1,2,3-三唑-4-基]甲基]氨基]-3-喹啉甲腈 |
| Canonical SMILES | N#CC1=C(C2=CC(NCC3=CN(CCN4CCCCCC4)N=N3)=CC(Cl)=C2N=C1)NC5=CC=C(F)C(Cl)=C5 |
| 分子式 | C27H27Cl2FN8 |
| 分子量 | 553.46 |
| 溶解度 | DMSO: 25 mg/mL (45.17 mM); Water:< 0.1 mg/mL (insoluble) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cot inhibitor-1 is a COT/Tpl2 inhibitor. [1]. Wu, Junjun et al Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-production in human whole blood.Bioorganic & Medicinal Chemistry Letters (2009), 19(13), 3485-3488. |
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