(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro).
| Cas No. | 581098-48-8 |
| Canonical SMILES | FC1=CC=C(C2=C(C3=CC=NC(N[C@@H](C)C4=CC=CC=C4)=C3)N=C(SC)N2)C=C1 |
| 分子式 | C23H21FN4S |
| 分子量 | 404.5 |
| 溶解度 | DMF: 20 mg/mL,DMSO: 12 mg/mL,Ethanol: 30 mg/mL,Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 µM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 µM, respectively). |
