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Ferulic Acid methyl ester
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ferulic Acid methyl ester图片
CAS NO:2309-07-1
包装与价格：
包装价格(元)
500mg询价
1g询价
5g询价

阿魏酸甲酯（Methyl ferulate）是阿魏酸的衍生物，从马铃薯中分离出来，具有抗炎和抗氧化的特性。
Cas No.2309-07-1
别名阿魏酸甲酯; Methyl ferulate
Canonical SMILESCOC1=C(O)C=CC(/C=C/C(OC)=O)=C1
分子式C11H12O4
分子量208.2
溶解度DMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties[1][2]. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders[1]. Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages[2].

Ferulic acid methyl ester (25 μg/mL) has no cytotoxic effects on BMDMs after treatment for 6 h, 18 h, 48 h[2].Ferulic acid methyl ester (Methyl ferulate; 5, 10, 25 μg/mL) suppresses TNFα, IL6, IFNγ but not IL10, inhibits NO generation at 10 and 25 μg/mL, in primary bone marrow derived-macrophages (BMDMs)[2].Ferulic acid methyl ester (25 μg/mL) inhibits COX-2 expression, blocks p-p38 and p-JNK[2].

References:
[1]. Sultana R. Ferulic acid ethyl ester as a potential therapy in neurodegenerative disorders. Biochim Biophys Acta. 2012 May;1822(5):748-52.
[2]. Phuong NT, et al. Anti-inflammatory activity of methyl ferulate isolated from Stemona tuberosa Lour. Asian Pac J Trop Med. 2014 Sep;7S1:S327-31.

 
 
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