TBHQ (tert-Butylhydroquinone) (tert-Butylhydroquinone) 是一种广泛使用的 Nrf2 激活剂，通过激活 Nrf2 防止阿霉素 (DOX) 诱导的心脏毒性。 TBHQ (tert-Butylhydroquinone) (tert-Butylhydroquinone) 也是一种 ERK 活化剂；在黑色素瘤中拯救 Dehydrocorydaline (DHC) 诱导的细胞增殖抑制。
| Cas No. | 1948-33-0 |
| 别名 | 特丁基对苯二酚; tert-Butylhydroquinone |
| Canonical SMILES | OC1=CC=C(O)C=C1C(C)(C)C |
| 分子式 | C10H14O2 |
| 分子量 | 166.22 |
| 溶解度 | DMSO : ≥ 56.66 mg/mL (340.87 mM) |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | TBHQ is an antioxidant that activates Nrf2. [1]. Sukumari-Ramesh S et al. Post-Injury Administration of Tert-butylhydroquinone Attenuates Acute Neurological Injury After Intracerebral Hemorrhage in Mice. J Mol Neurosci. 2016 Apr;58(4):525-31. [2]. Tert-butylhydroquinone ameliorates doxorubicin-induced cardiotoxicity by activating Nrf2 and inducing the expression of its target genes |
