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CC-90003
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CC-90003图片
CAS NO:1621999-82-3
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)询价
5mg询价
10mg询价
25mg询价
50mg询价
100mg询价

CC-90003是一种不可逆的,选择性的ERK1/2抑制剂,具有抗肿瘤活性。
Cas No.1621999-82-3
Canonical SMILESC=CC(NC1=CC(C)=CC=C1NC2=NC(NC3=CC(OC)=NC=C3C)=NC=C2C(F)(F)F)=O
分子式C22H21F3N6O2
分子量458.44
溶解度DMSO : ≥ 125 mg/mL (272.66 mM);Water :< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity.

CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity[1].

[1]. Monica M. Mita, et al. A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors. Journal of Clinical Oncology 35, no. 15_suppl (May 20 2017) 2577-2577.

 
 
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