FR 167653 (FR 167653硫酸盐) (FR 167653 (FR 167653硫酸盐))，一种具有口服活性和选择性的p38 MAPK抑制剂，是TNF-α的强效抑制剂；和 IL-1β；通过特异性抑制 p38 MAPK 活性产生。
| Cas No. | 158876-66-5 |
| 别名 | FR 167653 sulfate |
| Canonical SMILES | O=C(N1NC2=C(C3=CC=NC=C3)C(C4=CC=C(F)C=C4)=NN2CC1)C(C5=CC=CC=C5)=O.O=S(O)(O)=O |
| 分子式 | C24H20FN5O6S |
| 分子量 | 525.51 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | FR-167653 is a selective p38 MAPK inhibitor. [1]. Hattori S, et al. FR-167653, a selective p38 MAPK inhibitor, exerts salutary effect on liver cirrhosis through downregulation of Runx2. |
