EB-42486 是一种新型有效、高选择性的 G2019S-LRRK2 抑制剂(IC50< 0.2 nM)。
Cas No. | 2390475-81-5 |
分子式 | C22H22N8O |
分子量 | 414.46 |
溶解度 | DMSO : 250 mg/mL (603.19 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | EB-42486 is a novel, potent, and highly selective G2019S-LRRK2 inhibitor (IC50< 0.2 nM). [1]. Garofalo AW, et al. Selective Inhibitors of G2019S-LRRK2 Kinase Activity. J Med Chem. 2020 Dec 10;63(23):14821-14839. |