Syk-IN-1 (compound 4) 是一种有效的 Syk 抑制剂，IC50为 35 nM。
| Cas No. | 1491150-77-6 |
| Canonical SMILES | NC(C1=NN=C(N[C@@H]2CCCC[C@@H]2N)N=C1NC3=CC=CC4=C3NC=C4)=O |
| 分子式 | C18H22N8O |
| 分子量 | 366.42 |
| 溶解度 | DMSO : 100 mg/mL (272.91 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM[1]. References:
[1]. Thoma G, et al. Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg Med Chem Lett. 2015;25(20):4642-4647. |
