SU5204一种酪氨酸激酶抑制剂,对FLK-1(VEGFR-2)和HER2的IC50分别为4和51.5μM。
Cas No. | 186611-11-0 |
Canonical SMILES | O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=CC=C3OCC |
分子式 | C17H15NO2 |
分子量 | 265.31 |
溶解度 | DMSO: 100 mg/mL (376.92 mM) |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | SU5204, a tyrosine kinase inhibitor, has IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively[1]. [1]. Peng Cho Tang, et al. 3-heteroaryl-2-indolinone compounds for the treatment of disease. US5792783A. |