MDK34597（化合物 35）是一种有效的 PI3K p110α；抑制剂，pIC50 为 6.85。
| Cas No. | 371934-59-7 |
| 别名 | PIK抑制剂 |
| Canonical SMILES | NC1=CC=CC(C(N=C2N3CCOCC3)=NC4=C2OC5=NC=CC=C54)=C1 |
| 分子式 | C19H17N5O2 |
| 分子量 | 347.4 |
| 溶解度 | DMSO: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | MDK34697 is an inhibitor of PI3K p110α (IC50= 141.25 nM).1 1.Li, Y., Wang, Y., and Zhang, F.Pharmacophore modeling and 3D-QSAR analysis of phosphoinositide 3-kinase p110α inhibitorsJ. Mol. Model16(9)1449-1460(2010) |
