| CAS NO: | 112-86-7 |
| Cas No. | 112-86-7 |
| 别名 | 芥酸 |
| Canonical SMILES | CCCCCCCC/C=C\CCCCCCCCCCCC(O)=O |
| 分子式 | C22H42O2 |
| 分子量 | 338.57 |
| 溶解度 | DMSO: ≥ 100 mg/mL (295.36 mM); Water:< 0.1 mg/mL (insoluble) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia[1]. Erucic acid (oral administration; 3 mg/kg) enhances the phosphorylation level of PI3K, PKCζ, ERK, CREB and Akt in the hippocampus compared with that in the vehicle-treated control group[1]. Animal Model: Normal naÏve mice[1] [1]. Kim E, et al. The memory-enhancing effect of erucic acid on scopolamine-induced cognitive impairment in mice. Pharmacol Biochem Behav. 2016 Mar;142:85-90. |
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