Euphorbiasteroid 是续随子中的三环二萜，可抑制 tyrosinase 活性，增强 AMPK 的磷酸化，具有抗癌、抗病毒、抗肥胖及多重耐药调节作用。
| Cas No. | 28649-59-4 |
| 别名 | 千金子甾醇 |
| Canonical SMILES | CC(O[C@@](C[C@H](C)[C@@H]1OC(CC2=CC=CC=C2)=O)(C(/C(C)=C\[C@@H](C3(C)C)[C@@H]3CC[C@@]45CO5)=O)[C@@]1([H])[C@@H]4OC(C)=O)=O |
| 分子式 | C32H40O8 |
| 分子量 | 552.66 |
| 溶解度 | DMF: 5 mg/ml,DMSO: 5 mg/ml,Ethanol: Partially soluble |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Euphorbiasteroid is a tricyclic diperpene of Euphorbia lathyris L., inhibits tyrosinase, and increases the phosphorylation of AMPK, with anti-cancer, anti-virus, anti-obesity and multidrug resistance-modulating effect[1]. [1]. Park SJ, et al. Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells via activation of AMP-activated protein kinase. Cell Biochem Funct. 2015 Jun;33(4):220-5. |
