A cell-permeable fluorescent thallium indicator
| Cas No. | 1802991-71-4 |
| Canonical SMILES | O=C(C)OC1=CC=C2C3(C(C=CC(C(N([H])C4=CC(OC)=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C=C4)=O)=C5)=C5C(O3)=O)C6=CC=C(OC(C)=O)C=C6OC2=C1 |
| 分子式 | C42H36N2O17 |
| 分子量 | 840.7 |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Thallos AM is a cell-permeable fluorescent thallium indicator that has been used to measure the activity of sodium or potassium channels.1,2It can also be used for transporters and G protein-coupled receptors (GPCRs). It displays excitation/emission maxima of 490/515 nm, respectively. 1.Du, Y., Days, E., Romaine, I., et al.Development and validation of a thallium flux-based functional assay for the sodium channel NaV1.7 and its utility for lead discovery and compound profilingACS Chem. Neurosci.6(6)871-878(2015)
2.Dutter, B.F., Ender, A., Sulikowski, G.A., et al.Rhodol-based thallium sensors for cellular imaging of potassium channel activityOrg. Biomol. Chem.16(31)5575-5579(2018) |
