A metabolite of griseofulvin
Cas No. | 469-54-5 |
Canonical SMILES | O=C(CC(C1)=O)[C@@](C(C2=C3OC)=O)(OC2=C(C(OC)=C3)Cl)[C@@H]1C |
分子式 | C16H15ClO6 |
分子量 | 338.7 |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Griseofulvic acid is a metabolite of the antifungal griseofulvin .1It induces protein aggregation and tubulin polymerization in cell-free assays.2 1.Zia, H., O'Donnell, J.P., and Ma, J.K.Identification of griseofulvic acid as a urine metabolite of griseofulvin in humansJ. Pharm. Sci.68(10)1335-1336(1979)
2.Mir, L., Oustrin, M.-L., Lecointe, P., et al.Correlation between the in vivo effects of some griseofulvin derivatives and their in vitro interactions with mammalian microtubulesFEBS Lett.88(2)259-263(1978) |