A SARS-CoV entry inhibitor
Cas No. | 433212-75-0 |
Canonical SMILES | NC(N/N=C(C1=CC=CS1)/C)=S |
分子式 | C7H9N3S2 |
分子量 | 199.3 |
溶解度 | Ethanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | SSAA09E1 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) viral entry.1It reduces infection of HEK293T cells transiently transfected with angiotensin-converting enzyme 2 (ACE2) by an HIV-based virus system pseudotyped with SARS-CoV surface glycoprotein (EC50= 6.7 μM). SSAA09E1 also inhibits the proteolytic activity of cathepsin L (IC50= 5.33 µM) but not cathepsin B when used at a concentration of 20 µM. 1.() |