| CAS NO: | 72389-06-1 |
| 包装: | 1mg |
| 市场价: | 2858元 |
| Cas No. | 72389-06-1 |
| 别名 | 阿雷西霉素 |
| Canonical SMILES | O=C1C2=CC3=C([C@@H](O[C@H]4[C@H](OC)[C@H](O)[C@@H](O)[C@H](C)O4)[C@H](OC)[C@](C)(O)C3=O)C(O)=C2C(C5=C(O)C=CC=C51)=O |
| 分子式 | C27H28O12 |
| 分子量 | 544.5 |
| 溶解度 | Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Aranciamycin is a fungal metabolite that has been found inStreptomycesand has diverse biological activities.1,2It inhibitsC. histolyticumcollagenase but not elastase or trypsin in cell-free assays (IC50s = 0.37, >10, and >10 µM, respectively).1Aranciamycin is active againstM. bovisandB. subtilis(MICs = 30 and 15 µM, respectively).2It is cytotoxic to HepG2 cells (IC50= 18 µM). 1.Bols, M., Biderup, L., Hansen, J., et al.Inhibition of collagenase by aranciamycin and aranciamycin derivativesJ. Med. Chem.35(15)1768-2771(1992) 2.Khalil, Z.G., Raju, R., Piggott, A.M., et al.Aranciamycins I and J, antimycobacterial anthracyclines from an Australian marine-derived Streptomyces spJ. Nat. Prod.78(4)949-952(2015) |
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