CAS NO: | 7758-73-8 |
Cas No. | 7758-73-8 |
别名 | 5,7-二羟基-4-苯基香豆素 |
Canonical SMILES | OC1=C2C(OC(C=C2C3=CC=CC=C3)=O)=CC(O)=C1 |
分子式 | C15H10O4 |
分子量 | 254.24 |
溶解度 | DMSO: 250 mg/mL (983.32 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1]. [1]. Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Oct 30. |
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