包装 | 价格(元) |
5mg | 询价 |
10mg | 询价 |
25mg | 询价 |
50mg | 询价 |
Canonical SMILES | N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@@H](CC2=CC=CC=C2)C(N3[C@H](C(O)=O)CCC3)=O)=O)=O)=O)=O)CC4=CC=CC=C4.CC(O)=O |
分子式 | C36H48N6O7.XC2H4O2 |
分子量 | 676.8 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Hexapeptide-11 is a synthetic hexapeptide.1 Hexapeptide-11 (5% v/v) increases the expression of the antioxidant genes Nrf2, Keap1, NQO1, and TXNRD1 and decreases hydrogen peroxide-induced senescence of IMR-90 human lung fibroblasts in vitro. Hexapeptide-11 (5% v/v) increases the activity of matrix metalloproteinase-2 (MMP-2) and MMP-9 and the proteasome peptidases LLVY/β5 and LLE/β1 in IMR-90 cells in vitro and reduces the migration of IMR-90 cells in a scratch wound assay. |1. Sklirou, A.D., Ralli, M., Dominguez, M., et al. Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts. Redox Biol. 5, 205-215 (2015). |
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