Eupalinolide K 是一种来自野马追 (Eupatorium lindleyanum) 的倍半萜内酯化合物 (sesquiterpene lactones compound)，是 STAT3 抑制剂。Eupalinolide K 是一种迈克尔反应受体 (MRA)。
| Cas No. | 108657-10-9 |
| 别名 | 野马追内酯 K |
| Canonical SMILES | O=C(/C(C)=C/CO)O[C@H](C/C(C)=C\C[C@H](O)/C(C)=C\1)[C@](C2=C)([H])[C@]1([H])OC2=O |
| 分子式 | C20H26O6 |
| 分子量 | 362.42 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1].
STAT3 [1]. Yang B, , et al. Precise discovery of a STAT3 inhibitor from Eupatorium lindleyanum and evaluation of its activity of anti-triple-negative breast cancer. Nat Prod Res. 2019 Feb;33(4):477-485. |
