JAK3-IN-7是一种有效的选择性JAK3抑制剂,详细信息请参考专利文献WO2011013785A1中表1-1中的化合物1和2,IC50<0.01μM。
Cas No. | 1263774-57-7 |
Canonical SMILES | N#CCC(N1CC(C)C12CN(C3=C4C(NC=C4)=NC=N3)CCC2)=O |
分子式 | C17H20N6O |
分子量 | 324.38 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | JAK3-IN-7 is a potent and selective JAK3 inhibitor extracted from patent WO2011013785A1, has an IC50 of<0.01 μM. [1]. NOJI, Satoru, et al. NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME. WO2011013785A1. |