Btk inhibitor 1 R enantiomer hydrochloride 是依鲁替尼的杂质。 IBT6A 可用于 IBT6A 依鲁替尼二聚体和 IBT6A 加合物的合成。 Ibrutinib 是一种选择性、不可逆的 Btk 抑制剂，IC50 为 0.5 nM。
| Cas No. | 1553977-42-6 |
| 别名 | 3-(4-苯氧基苯基)-1-(3R)-3-哌啶基-1H-吡唑并[3,4-D]嘧啶-4-胺盐酸盐(1:1) |
| Canonical SMILES | NC1=C2C(N([C@H]3CNCCC3)N=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1.Cl |
| 分子式 | C22H23ClN6O |
| 分子量 | 422.91 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Btk inhibitor 1R enantiomer Hcl is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.IC50 value:Target: BtkFrom PCT Int. Appl. (2012), WO 2012158843 A2 20121122. [1]. PCT Int. Appl. (2012), WO 2012158843 A2 20121122. |
