KRAS G12C inhibitor 14 是一种有效的 KRAS G12C 抑制剂，IC50 为 18 nM，详细信息请参考专利文献 WO2019110751A1 中的化合物 17。
| Cas No. | 2349393-95-7 |
| 分子式 | C24H19ClF2N4O3 |
| 分子量 | 484.88 |
| 溶解度 | DMSO : 100 mg/mL (206.24 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 17, has an IC50 of 18 nM[1]. [1]. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1. |
