CAS NO: | 2226517-75-3 |
包装 | 价格(元) |
5mg | 询价 |
25mg | 询价 |
Cas No. | 2226517-75-3 |
Canonical SMILES | ClC1=CC=C(C2(C3=NN4C(NC(C5=CC(I)=CC=C45)=O)=C3C#N)CC2)C=C1 |
分子式 | C20H12ClIN4O |
分子量 | 486.7 |
溶解度 | DMSO|9.73|20| |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Dynein inhibitor. Inhibits dynein 1 and dynein 2-dependent microtubule gliding (IC50 values are 2.3 and 2.6 μM, respectively). Inhibits hedgehog signaling in vitro (IC50 = 1.9 μM). Displays reversible inhibition of retrograde and anterograde intraflagellar transport in Chlamydomonas; displays stronger inhibition of retrograde transport. |
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