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8Br-HA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
8Br-HA图片
包装与价格:
包装价格(元)
5mg询价
10mg询价
25mg询价

An FHIT inhibitor
Canonical SMILESO=C(OC1=C2C=CC(OCC(NO)=O)=C1Br)C3=C2CCCC3
分子式C15H14BrNO5
分子量368.2
溶解度DMF: 10 mg/ml,DMSO: 10 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT; IC50= 0.12 µM).1It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 µM, respectively).

1.Kawaguchi, M., Sekimoto, E., Ohta, Y., et al.Synthesis of fluorescent probes targeting tumor-suppressor protein FHIT and Identification of apoptosis-inducing FHIT inhibitorsJ. Med. Chem.64(13)9567-9576(2021)

 
 
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