| 包装 | 价格(元) |
| 10mg | 询价 |
| 25mg | 询价 |
| 50mg | 询价 |
| 100mg | 询价 |
| Canonical SMILES | C[C@@H](O)[C@H](N)C(N[C@@H](CCCCN)C(N1[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CCC1)=O)=O.OC(C(F)(F)F)=O |
| 分子式 | C21H40N8O6·XCF3COOH |
| 分子量 | 500.6 |
| 溶解度 | DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Tuftsin is an endogenous peptide generated by proteolysis of leukokinin that stimulates phagocytosis.1It binds human polymorphonuclear leukocytes (PMN), human monocytes, and mouse macrophages with Kdvalues of 130, 125, and 53 nM, respectively.2Tuftsin (200 nM) increases phagocytosis of IgG-coated ovine red blood cells by 61% in isolated mouse peritoneal macrophages. It increases phagocytosis of the bacteriaS. aureusandL. monocytogenes, as well as the fungusS. oviformis, by isolated human, mouse, rabbit, dog, or guinea pig phagocytes when used at concentrations ranging from 0.01 to 0.15 µg/ml.3Tuftsin (0.1, 0.5, and 25 mg/kg) increases survival in a syngeneic mouse model of 2-methylcholanthrene-induced fibrosarcoma.4 1.Najjar, V.A., and Nishioka, K."Tuftsin": A natural phagocytosis stimulating peptideNature228(5272)672-673(1970) 2.Gottlieb, P., Stabinsky, Y., Hiller, T., et al.Tuftsin receptorsAnn. N. Y. Acad. Sci.41993-106(1983) 3.Martinez, J., and Winternitz, F.Bactericidal activity of tuftsinMol. Cell Biochem.41123-136(1981) 4.Catane, R., Schlanger, S., Weiss, L., et al.Toxicology and antitumor activity of tuftsinAnn. N. Y. Acad. Sci.419251-260(1983) |
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