A glucose derivative with anticancer activity
| Cas No. | 29702-43-0 |
| 别名 | 2-脱氧-2-氟-D-葡萄糖 |
| Canonical SMILES | OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](F)C=O |
| 分子式 | C6H11FO5 |
| 分子量 | 182.1 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 2-deoxy-2-fluoro-D-Glucose (2-FG) is a derivative of glucose with anticancer activity.1It inhibits the growth of 143B osteosarcoma cells grown under normoxic and hypoxic conditions when used at concentrations of 6 and 24 mM. 1.Lampidis, T.J., Kurtoglu, M., Maher, J.C., et al.Efficacy of 2-halogen substituted ?-glucose analogs in blocking glycolysis and killing ''hypoxic tumor cells''Cancer Chemother. Pharmacol.58(6)725-734(2006) |
