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Desmopressin(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Desmopressin(trifluoroacetate salt)图片
包装与价格:
包装价格(元)
500 µg询价
1mg询价
5mg询价

A vasopressin receptor agonist
Canonical SMILESNC(CNC([C@@H](CCCNC(N)=N)NC([C@@H]1CCCN1C([C@H](CSSCCC(N[C@@H](CC2=CC=C(O)C=C2)C3=O)=O)NC([C@H](CC(N)=O)NC([C@@H](NC([C@@H](N3)CC4=CC=CC=C4)=O)CCC(N)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
分子式C46H64N14O12S2• XCF3COOH
分子量1069.2
溶解度DMF: 1 mg/ml,DMSO: 5 mg/ml,PBS (pH 7.2): 2 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Desmopressin is a synthetic version of the endogenous antidiuretic hormone arginine vasopressin (AVP). Compared to AVP, the first amino acid of desmopressin has been deaminated, and the arginine at the eighth position is in the dextrorotatory rather than the levorotatory form. Desmopressin acts as an agonist at human vasopressin V1a, V1b, and V2receptors with Kivalues of 62.4, 5.8, and 23.3 nM, respectively.1

1.Cheng, L.L., Stoev, S., Manning, M., et al.Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4J. Med. Chem.47(9)2375-2388(2004)

 
 
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