CIN-16645 是一种阳离子脂质，可用于将生物活性剂递送至细胞和组织（摘自专利 WO2015095340 A1）。
| Cas No. | 1799316-64-5 |
| Canonical SMILES | CCCCCCCCOC(OCCCCCCCC)CCC(OCC(COC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(OCCCN(CC)CC)=O)=O |
| 分子式 | C50H93NO9 |
| 分子量 | 852.3 |
| 溶解度 | Dichloromethane: soluble,DMF: soluble,DMSO: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CIN-16645 is an ionizable amino lipid.1It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) to deliver single-guide RNA (sgRNA) targeting MHC class II transactivator (CIITA) in T cells. 1.Sridhar, S., Zhang, Y., Harrington, W.F., et al.Compositions and methods for reducing MHC class II in a cell(2022) |
