A synthetic lipolytic peptide
| Cas No. | 221231-10-3 |
| Canonical SMILES | OC(C=C1)=CC=C1C[C@H](N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]2C(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CSSC2)C(NCC(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)=O)=O)CO)=O)=O)CCC(O)=O)=O)C(C)C)=O)CO)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O |
| 分子式 | C78H123N23O23S2 |
| 分子量 | 1815.1 |
| 溶解度 | DMSO: Slightly soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | AOD-9604 is a synthetic lipolytic 15-amino acid peptide fragment derived from human growth hormone.1,2In vivo, AOD-9604 (250 µg/kg per day) decreases body weight, epididymal adipose tissue mass, and brown adipose tissue weight inob/obmice.1It also enhances cartilage regeneration in a rabbit model of collagenase-induced knee osteoarthritis.2 1.Heffernan, M., Summers, R.J., Thorburn, A., et al.The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and β3-AR knock-out miceEndocrinology142(12)182-189(2001)
2.Kwon, D.R., and Park, G.Y.Effect of intra-articular injection of AOD9604 with or without hyaluronic acid in rabbit osteoarthritis modelAnn. Clin. Lab. Sci.45(4)426-432(2015) |
