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7-(β-Hydroxyethyl)theophylline-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-(β-Hydroxyethyl)theophylline-d6图片
包装与价格:
包装价格(元)
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An internal standard for the quantification of 7-(β-hydroxyethyl)theophylline
Canonical SMILESO=C1N(C([2H])([2H])[2H])C(C(N(CCO)C=N2)=C2N1C([2H])([2H])[2H])=O
分子式C9H6D6N4O3
分子量230.3
溶解度Chloroform: soluble,Methanol: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

7-(β-Hydroxyethyl)theophylline-d6is intended for use as an internal standard for the quantification of 7-(β-hydroxyethyl)theophylline by GC- or LC-MS. 7-(β-Hydroxyethyl)theophylline is a methylxanthine phosphodiesterase (PDE) inhibitor.1It reduces histamine, 5-hydroxytryptamine (5-HT), and bradykinin-induced bronchoconstriction in an anesthetized guinea pig model of bronchial asthma.2Formulations containing 7-(β-hydroxyethyl)theophylline in combination with theophylline have been used in the treatment of asthma.

1.Mizon, J., Skandrani, E., and Mizon, C.Determination of the inhibitory activity of some new substituted theophyllines on the specific phosphodiesterase of cyclic nucleotidesTherapie26(5)911-917(1971) 2.Ufkes, J.G., Leeuwin, R.S., Ottenhof, M., et al.Efficacy of theophylline and its N-7-substituted derivatives in experimentally induced bronchial asthma in the guinea-pigArch. Int. Pharmacodyn. Ther.253(2)301-314(1981)

 
 
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