TAK-653 是一种具有 AMPA 受体激动活性的化合物,在大鼠体内产生抗抑郁样作用,具有良好的安全性。
Cas No. | 1358751-06-0 |
别名 | 9-(4-(环己氧基)苯基)-7-甲基-3,4-二氢吡嗪[2,1-C][1,2,4]噻二嗪-2,2-二氧化物 |
分子式 | C19H23N3O3S |
分子量 | 373.47 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats. [1]. Hara H, et al. TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats. Pharmacol Biochem Behav. 2021 Dec;211:173289. |