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NT1-O14B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NT1-O14B图片
CAS NO:2739805-64-0
包装与价格:
包装价格(元)
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A cationic lipidoid
Cas No.2739805-64-0
Canonical SMILESO=C(OCCSSCCCCCCCCCC)CCN(CCC1=CNC2=C1C=CC=C2)CCC(OCCSSCCCCCCCCCC)=O
分子式C40H68N2O4S4
分子量769.2
溶解度Ethanol: Soluble
储存条件-20буC
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NT1-O14B is a tryptamine-containing cationic lipidoid.1It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing NT1-O14B and encapsulating antisense nucleotides against tau decreases tau brain levels in mice.

1.Ma, F., Yang, L., Sun, Z., et al.Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injectionSci. Adv.6(30)eabb4429(2020)

 
 
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