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HN37
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
HN37图片
CAS NO:1821222-10-9
包装与价格:
包装价格(元)
5mg询价
10mg询价

HN37 是有效且稳定的抗癫痫活性的化合物,其对 KCNQ2 的 EC50 值为 37 nM。
Cas No.1821222-10-9
分子式C20H21FN2O2
分子量340.39
溶解度DMSO : 50 mg/mL (146.89 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

HN37 as a potent and chemically stable antiepileptic drug candidate, with an EC50 of 37 nM for KCNQ2[1].

HN37 is a potent neuronal Kv7 activator with a subtype selectivity similar to RTG[1].

[1]. Yang-Ming Zhang, et al. Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate. J Med Chem. 2021 May 13;64(9):5816-5837.

 
 
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