KCNQ1 activator-1 (compound 3) 是一种有效的 KCNQ1 通道激活剂。KCNQ1 activator-1 具有研究长QT综合征 (LQTS) 的潜力。
Cas No. | 1008671-38-2 |
分子式 | C22H23N3O4S2 |
分子量 | 457.57 |
溶解度 | DMSO : 250 mg/mL (546.36 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | KCNQ1 activator-1 (compound 3) is a potent activator of KCNQ1 channel. KCNQ1 activator-1 has the potential for the research of long QT syndrome (LQTS)[1]. [1]. Mattmann ME, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941. |