KM91104 是一种细胞通透性 V-ATPase 抑制剂，专门针对 V-ATPase 的 a3-b2 亚单位。
| Cas No. | 304481-60-5 |
| 分子式 | C14H12N2O4 |
| 分子量 | 272.26 |
| 溶解度 | DMSO : 100 mg/mL (367.30 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | KM91104, a cell-permeable V-ATPase inhibitor, specifically targets the a3-b2 subunits of V-ATPase[1]. [1]. Marrone G, et al. The adenosine monophosphate-activated protein kinase-vacuolar adenosine triphosphatase-pH axis: A key regulator of the profibrogenic phenotype of human hepatic stellate cells. Hepatology. 2018;68(3):1140-1153.
[2]. GÖttle P, et al. Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination. Glia. 2019;67(1):160-170. doi:10.1002/glia.23535 |
