A potential impurity found in bulk preparations of lansoprazole
| Cas No. | 213476-12-1 |
| 别名 | 2-[[[3-甲基-1-氧代-4-(2,2,2-三氟乙氧基)-2-吡啶]甲基]亚硫酰基]苯并咪唑 |
| Canonical SMILES | O=S(C1=NC2=CC=CC=C2N1)CC3=C(C)C(OCC(F)(F)F)=CC=[N]3=O |
| 分子式 | C16H14F3N3O3S |
| 分子量 | 385.4 |
| 溶解度 | DMSO: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Lansoprazole N-oxide is a potential impurity found in bulk preparations of the proton pump inhibitor lansoprazole.1It is a degradation product formed under acid or base stress. 1.Rao, P.V., Kumar, M.N., and Kumar, M.R.A novel, validated stability-indicating UPLC method for the estimation of lansoprazole and its impurities in bulk drug and pharmaceutical dosage formsSci. Pharm.81(1)183-193(2013) |
