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Fluo-2 AM
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fluo-2 AM图片
CAS NO:1070771-36-6
包装与价格:
包装价格(元)
1mg询价
20 x 50 µg询价

A cell-permeable fluorescent calcium indicator
Cas No.1070771-36-6
别名钙离子荧光探针FLUO-2AM
Canonical SMILESO=C1C=CC2=C(C3=CC(OCCOC4=CC(C)=CC=C4N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C=C3)C5=C(C=C(C=C5)OCOC(C)=O)OC2=C1
分子式C51H52N2O23
分子量1061
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fluo-2 AM is a cell-permeable fluorescent calcium indicator.1,2It has been used to measure the activity of the neuropeptide Y4receptor, as well as to detect intracellular calcium in tetrandine-stimulated primary rabbit corpus cavernosum smooth muscle cells. It binds to calcium (Kd= 290 nM) and displays excitation/emission maxima of 490/515 nm, respectively. Fluo-2 AM is also available in a cell-impermeable form .

1.Sliwoski, G., Schubert, M., Stichel, J., et al.Discovery of small-molecule modulators of the human Y4 receptorPLoS One11(6)e0157146(2016) 2.Liu, J.-H., Chen, J., Wang, T., et al.Effects of tetrandrine on cytosolic free calcium concentration in corpus cavernosum smooth muscle cells of rabbitsAsian J. Androl.8(4)405-409(2006)

 
 
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