包装: | 1mg |
市场价: | 6804元 |
Canonical SMILES | COC1=CC(CCN2C([2H])([2H])C([2H])([2H])C([2H])([2H])NC[C@@H]3C4=CC(OC)=C(C=C4C3)OC)=C(CC2=O)C=C1OC.Cl |
分子式 | C26H28D6N2O5·HCl |
分子量 | 497.1 |
溶解度 | Methanol: soluble |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | rac-N-desmethyl Ivabradine-d6is intended for use as an internal standard for the quantification of N-desmethyl ivabradine by GC- or LC-MS. N-desmethyl Ivabradine is an active metabolite of ivabradine .1Ivabradine is metabolized by the cytochrome P450 (CYP) isoform CYP3A4. 1.Rosa, G.M., Ferrero, S., Ghione, P., et al.An evaluation of the pharmacokinetics and pharmacodynamics of ivabradine for the treatment of heart failureExpert Opin. Drug Metab. Toxicol.10(2)279-291(2014) |
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