A potential impurity found in commercial preparations of lacosamide
| Cas No. | 196601-69-1 |
| 别名 | (2R)-2-氨基-3-甲氧基-N-(苯基甲基)丙酰胺 |
| Canonical SMILES | COC[C@@H](N)C(NCC1=CC=CC=C1)=O |
| 分子式 | C11H16N2O2 |
| 分子量 | 208.3 |
| 溶解度 | DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Descarbonyl-lacosamide is a potential impurity found in commercial preparations of lacosamide .1It is a degradation product formed under acidic conditions.2 1.Molleti, S., Rao, V., and Jayaveera, K.N.Stability indicating RP-UPLC method for the determination of lacosamide and its impurities in bulk drugs and its pharmaceutical dosage formsDer Pharma Chemica5(1)81-89(2013)
2.Tiwari, R.N., and Bonde, C.G.Identification and characterization of degradation products of lacosamide by liquid-chromatography/time-of-flight mass spectrometric and multi-stage mass spectrometric analysisJ. Liq. Chromatogr.37(14)2046-2061(2014) |
