A potential impurity found in commercial preparations of olanzapine
Cas No. | 221176-49-4 |
别名 | 奥氮平相关物质B |
Canonical SMILES | O=C1NC2=C(NC3=C1C=C(C)S3)C=CC=C2 |
分子式 | C12H10N2OS |
分子量 | 230.3 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 15 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Olanzapine-related compound B is a potential impurity found in commercial preparations of olanzapine.1It is a degradation product formed by exposure to oxidative stress. 1.Hiriyanna, S.G., Basavaiah, K., Goud, P.S.K., et al.Identification and characterization of olanzapine degradation products under oxidative stress conditionsActa Chromatagr.20(1)81-93(2008) |