Thalidomide-NH-C10-COOH (compound 6b) 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于Thalidomide 的 von Hippel-Lindau (VHL) 配体和 1 个 linker。
| Cas No. | 2428400-33-1 |
| 分子式 | C24H31N3O6 |
| 分子量 | 457.52 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Thalidomide-NH-C10-COOH (compound 6b) is a synthesizedE3 ligase ligand-linker conjugatethat incorporates the Thalidomide based von Hippel-Lindau (VHL) ligand and a linker used in PROTAC technology[1]. [1]. Kim K, et al. Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci Rep. 2019 Dec 23;9(1):19654. |
