Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2055042-69-6

包装与价格：

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB 是一种可降解 (cleavable) 的含 3 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

Cas No.	2055042-69-6
分子式	C₆₀H₆₆N₆O₁₁
分子量	1047.2
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1]. [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.